Ray Wise plays The Devil on Reaper.

In the late sixties and seventies, Wise played attorney Jamie Rollins on the soap opera, Love of Life. He also appeared on Twin Peaks, as Liko in the Star Trek: The Next Generation episode "Who Watches the Watchers," as California governor Gabriel Tillman on The West Wing, Vice President Hal Gardner on 24.

For film, Wise played 1950s CBS News anchor Don Hollenbeck in George Clooney's Good Night, and Good Luck, Peaceful Warrior with Nick Nolte, RoboCop and Swamp Thing.

For gaming, he played the United States President in Command & Conquer Red Alert 2 and it's expansion pack, Yuri's Revenge.